Introduction
Amyloidosis is a disease characterized by the deposition of altered oteins in tissues that shows the following characteristics: beta-pleated sheet molecular configuration with affinity to Congo red dye, fibrillar ultrastructure, and presence in the extracellular matrix leading to hardening of the affected tissues. Depending upon its extent, amyloidosis can be classified as systemic or localized disease. The reason for localized deposition is unknown, but it is hypothesized that such deposits result from the local synthesis of amyloid proteins rather than the deposition of light chains produced elsewhere. Isolated localized amyloidosis has been reported in almost every organ system. The localized form presents minor clinical manifestations as compared to the extensive organ involvement observed in systemic disease, and local amyloidosis may not be progressive [1]. Worldwide, there are few case report concerning localized amyloidosis of the penile shaft [2,3], and only a few reports o localized amyloidosis of the glans penis in Korea. We report here a rare case of localized amyloidosis of the penile shaft that manifested as urethral obstruction due to amyloid infiltration.