Articles
A Review of Type 2 Diabetes Drug Classes
Both insulin and glucagon levels are influenced by incretin hormones: glucagon-like peptide-1 (GLP-1), which is secreted by the intestinal...
A United Nations Resolution on Diabetes The Result of a Joint Effort
Resolution 61/225: ‘World Diabetes Day’ recognizes diabetes as a chronic, debilitating, and costly disease associated with major...
Adding to the Armamentarium for the Treatment of Diabetes Mellitus
It is now well established that improving glycemic control reduces the risk of microvascular complications, but optimal glycemic control has been...
Advances in Diabetes Diagnostics
According to the last American Diabetes Association (ADA) recommendations, it is possible to demonstrate an abnormality in carbohydrate metabolism,...
Advances in Diabetic Retinopathy
Pathogenesis of Diabetic Retinopathy Diabetes-associated Retinal Dysfunctions Before the Onset of Clinical Diabetic Retinopathy Abnormalities in...
Advances in Insulin Therapy Physiological Replacement with Insulin Analogs
All insulin currently manufactured for therapeutic purposes in the US is made through recombinant DNA technology. Alterations to the basic human...
Advances in the Genetics of Type 2 Diabetes Mellitus in the Light of Personalized Healthcare
Clinical Complexity of Type 2 DiabetesClinically, one can distinguish three states—normal, impaired glucose tolerance, and overt...
Advances in Understanding Glucose Variability and the Role of Continuous Glucose Monitoring
Evidence from several large randomised clinical trials has linked glycated haemoglobin (HbA1c) to vascular diabetes complications.1,2 Consequently,...
Advancing Beyond Basal Insulin Therapy in Patients with Type 2 Diabetes
People with T2D will eventually need insulin therapy because oral agents fail over time. Although we have data spanning decades demonstrating that...
Advancing Insulin Therapy—An Insulin Pump or a Basal–Prandial Insulin Regimen?
There are many reasons for suboptimal use of insulin, and these include fears of hypoglycemia and weight gain and both physician and patient...
Aggressive Management of Blood Glucose
We definitely have the personnel, tools, and resources to achieve our goals. Once the diagnosis of diabetes is established, we must provide a...
Alpha-cell Function in Type 2 Diabetes
The Facts Glucagon plasma levels are usually grossly elevated in diabetic ketoacidosis, hyper-osmolar non-ketotic coma and poorly controlled...
Angiotensin Receptor Blockers and Type 2 Diabetic Nephropathy
Long-term complications of diabetes include increased risk of cardiovascular disease and the development of small-vessel (microvascular)...
Anti-diabetic Treatment in Obese Patients with Type 2 Diabetes Effects of Medication on Body Weight
One of the challenges of using anti-diabetic therapy in obese or overweight patients is the prospect of substantial iatrogenic weight gain with many...
As Use of Herbal Remedies Soars, Patients Taking These and Cardiovascular Medications May be at Heightened Risk of Dangerous, Potentially Life-Threatening Interactions
"Many people have a false sense of security about these herbal products because they are seen as 'natural,'" said Arshad Jahangir, M.D.,...
ASU and Mayo Clinic Partner to Combat Metabolic Syndrome
Physicians, scientists and clinicians at the new ASU/Mayo Center for Metabolic and Vascular Biology will work together on solutions for this...
Attaining Treatment Goals as a Measure of Therapy Benefits in Type 2 Diabetes
The Diabetes Control and Complications Trial (DCCT)3 and the United Kingdom Prospective Diabetes Study (UKPDS)4,5 demonstrated the benefits of...
Autonomic Neuropathy Is Treatable
Regardless of what the condition is called, and contrary to the common misperception, autonomic dysfunction is treatable. However, the earlier the...
Basal InslinMyths and Realities
There is a high prevalence of mixed dyslipidaemia among patients with metabolic syndrome or diabetes mellitus.1 This highly atherogenic phenotype,...
Beta-cell Defects in Type 2 Diabetes and the Possibility of Treatment Options with GLP-1-based Therapies
In the development of type 2 diabetes, environmental influences (most importantly diet and sedentary lifestyle) and genetic factors lead to the...
