Articles

Advances in Our Understanding of Hyperthyroidism-associated Bone Loss

Hyperthyroidism is an important cause of secondary osteoporosis2 and the relationship between the hypothalamic–pituitary– thyroid (HPT)...

Advances in the Diagnosis and Management of Differentiated Thyroid Cancer

Despite an increasing incidence, the mortality from thyroid cancer in general and from papillary thyroid cancer in particular remained stable (0.5...

Advances in the Management of Differentiated Thyroid Cancer—Is There an Optimal Regimen?

Etiology Approximately 75% of thyroid cancer cases are papillary thyroid carcinomas (PTC), while approximately 10% are follicular thyroid carcinomas...

Advances in the Treatment of Differentiated Thyroid Cancer

In both papers, new tools introduced in the last 10 years have been integrated Both the American and European expert panels propose a risk-dependent...

Advances in the Treatment of Graves’ Disease – A Focus on Rituximab

Current therapies of Graves’ disease are aimed at reducing thyroid hormone synthesis and consist of thionamides, radioiodine and surgery.6...

As Use of Herbal Remedies Soars, Patients Taking These and Cardiovascular Medications May be at Heightened Risk of Dangerous, Potentially Life-Threatening Interactions

"Many people have a false sense of security about these herbal products because they are seen as 'natural,'" said Arshad Jahangir, M.D.,...

Consequences of the Use of Low Blood-spot Thyroid-stimulating Hormone Cut-offs for the Neonatal Screening of Congenital Hypothyroidism

Congenital hypothyroidism (CH) is the most common congenital endocrine disease and avoidable cause of severe mental retardation. L-thyroxine...

Focus on Primary Hyperparathyroidism – Diagnosis, Management and the Role of Calcimimetics

Primary Hyperparathyroidism – An Evolving Disorder Primary hyperparathyroidism (HPT) is a common endocrine disease characterised by...

Guideline-orientated Diagnosis of Thyroid Nodules

Aetiology, Epidemiology and Risks Thyroid nodules are very common. Moreover, with the increasing use of sensitive imaging techniques, an increasing...

How Iodide Reaches its Site of Utilisation in the Thyroid Gland Involvement of Solute Carrier 26A4 (Pendrin) and Solute Carrier 5A8 (Apical Iodide Transporter)

This concentration gradient may be more than 100:1 in a hyperactive thyroid, as seen in patients with Graves’ disease. The daily intake of an...

Hypothyroidism Talking Points 2006

Much has happened since then. Kendall discovered thyroxine in 1914. Dietary iodine supplementation followed Marine and Kimball’s work on the...

Management of Patients with Differentiated Thyroid Cancer

Questions remain unanswered concerning differentiated-thyroid carcinoma •    What is the role and optimal extent of surgery?...

Managing Discordant Thyroid Function Tests

Normal PhysiologyThe hypothalamo-pituitary-thyroid axis is under tightly regulated feedback control involving the thyrotropin releasing hormone...

Mayo Clinic Tests Non-Incision, Endoscopic Ulcer Repair

"Laparoscopic surgery for this condition is only 80 percent successful for a variety of reasons," says Juliane Bingener, M.D., senior author on...

Medical Management of Hyperthyroidism

Medical Management of HyperthyroidismAntithyroid drugs and radioactive iodine (RAI) remain the mainstay of medical treatment for patients with GD or...

Multinodular Goiter—Diagnostic and Treatment Considerations

The evaluation of a patient with a palpable solitary nodule is generally straightforward and usually will include a fine-needle aspiration (FNA)...

Resistance to Thyroid Hormone and Cardiovascular Risk

Thyroid Hormones and the Heart The heart represents an important target for thyroid hormones (TH).1 Both transcriptional and non-transcriptional...

Significance of Fine-needle Aspiration Biopsy in the Pre-operative Diagnostics of the Thyroid Gland

Methodology of FNAB of the ThyroidFNAB of the thyroid is preceded by palpation of the gland and U/S examination. Data from clinical and U/S...

Subclinical Hypothyroidism—The Treatment Controversy

To develop an evidence-based approach to many unresolved issuesregarding subclinical thyroid disease, the American Association of Clinical...

The management of acute parathyroid crisis secondary to parathyroid carcinoma: a case report

Introduction Hypercalcaemic hyperparathyroid crisis is a rare but life-threatening complication of primary hyperparathyroidism. The symptoms of...

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