John B Buse, MD, PhD, is the Verne S Caviness Distinguished Professor, Chief of the Division of Endocrinology, Director of the Diabetes Center, Director of the North Carolina (NC) Translational and Clinical Sciences Institute, and Executive Associate Dean for Clinical Research at the University of North Carolina (UNC) School of Medicine in Chapel Hill. He has been on the faculty at UNC since 1994 and has received international recognition for innovative patient-centered care. He works with teams of investigators in diabetes clinical trials, comparative effectiveness research, and translation of basic science towards clinical application. Dr Buse serves as Director of the NC Translational and Clinical Sciences Institute working through a National Institutes of Health (NIH)-based consortium to accelerate the conversion of ideas and discoveries to products and policies for the improvement of health and well-being. Dr Buse completed service as President for Medicine & Science at the American Diabetes Association in 2008 and as Chair of the National Diabetes Education Program in 2014. He has received numerous awards and honors, including the 2010 Castle Connolly National Physician of the Year Award. He has authored more than 300 publications in journals including The New England Journal of Medicine, JAMA, and Diabetes Care. Dr Buse received his MD and PhD from Duke University before training in internal medicine and endocrinology at the University of Chicago.