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Contents
Foreword
Martin Silink, MD, FRACP 10
Professor of Pediatric Endocrinology, University of Sydney and The Children’s Hospital at Westmead
Current Issues International Health and Diabetes
Diabetes and Tuberculosis—Old Associates Posing a Renewed Public Health Challenge 12
Anil Kapur, MD,
1
Anthony D Harries, MD,
2
Knut Lönnroth, MD, PhD,
3
Ib C Bygbjerg, MD
4
and
Pierre Lefèbvre, MD, PhD
5
1. Managing Director, World Diabetes Foundation; 2. Senior Advisor, International Union Against Tuberculosis and Lung Diseases;
3. Medical Officer, Stop TB Department, World Health Organization; 4. Professor, Department of International Health, Immunology,
and Microbiology, University of Copenhagen; 5. Emeritus Professor of Medicine, University of Liège
Diabetes in Sub-Saharan Africa—Overview of a Looming Health Challenge 15
Felix K Assah, MD, MPhil
1
and Jean-Claude Mbanya, MD, PhD, FRCP
2
1. Doctoral Student, MRC Epidemiology Unit, Institute of Metabolic Science, Addenbrooke’s Hospital, Cambridge;
2. Professor of Medicine and Endocrinology, Department of Internal Medicine and Specialities,
Faculty of Medicine and Biomedical Sciences, University of Yaoundé I
International Diabetes Federation—The Global Voice for Diabetes 20
Ann Keeling
Chief Executive Officer, International Diabetes Federation (IDF)
Diabetes Prevention
The Importance of Testing for Pre-diabetes—Using the Right Tool 22
Olga S Chajewski, MD
1
and James H Nichols, PhD, DABCC, FACB
2
1. Pathology Resident, Baystate Medical Center; 2. Professor of Pathology, Tufts University School of Medicine, and
Medical Director, Clinical Chemistry, Department of Pathology, Baystate Health System
Doing More with What We Already Know—Prevention and Improved Coverage of
Healthcare for Diabetes 26
David Whiting, PhD
Epidemiologist and Public Health Specialist, International Diabetes Federation (IDF)
‘Too Much Sitting’ and Metabolic Risk—Has Modern Technology Caught Up with Us? 29
David W Dunstan, PhD,
1,2,3,4,5
Genevieve N Healy, PhD,
1,3
Takemi Sugiyama, PhD
3
and
Neville Owen, PhD
3
1. Baker IDI Heart and Diabetes Institute, Melbourne; 2. Department of Epidemiology and Preventive Medicine,
Monash University, Melbourne; 3. Cancer Prevention Research Centre, School of Population Health, The University of Queensland;
4. School of Exercise and Nutrition Sciences, Deakin University, Melbourne; 5. Vario Health Institute, Edith Cowan University, Perth
Diabetes Pathophysiology
The Role of Insulin in the Regulation of PEPCK and Gluconeogenesis In Vivo 34
Christopher J Ramnanan, PhD,
1
Dale S Edgerton, PhD
2
and Alan D Cherrington, PhD
3
1. Post-doctoral Fellow; 2. Research Assistant Professor; 3. Professor, Department of Molecular Physiology and Biophysics,
Vanderbilt University School of Medicine
Diabetes Management
Progression from Basal to Pre-mixed or Rapid-acting Insulin—
Options for Intensification and the Use of Pumps 40
Morali D Sharma, MD
1
and Alan J Garber, MD, PhD
2
1. Associate Professor of Medicine; 2. Professor of Medicine, Biochemistry, and Molecular Biology, and
Molecular and Cellular Biology, Division of Diabetes, Endocrinology, and Metabolism, Baylor College of Medicine
Glucose Control in the Critically Ill Patient Utilizing Computerized Intravenous Insulin Dosing 45
Samuel E Crockett, MD
Associate Professor of Medicine, Department of Medical Education, University of Central Florida College of Medicine
4 US ENDOCRINOLOGY
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