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Contents
The Importance of Good Insulin Injection Practices in Diabetes Management 49
Richard Dolinar, MD
Clinical Endocrinologist, Arizona Endocrinology Center
The Role of Gastrointestinal Metabolic Surgery in the Management of Type 2 Diabetes 53
Federica del Genio, MD, PhD,
1
Gladys Witt Strain, PhD, RD
2
and Francesco Rubino, MD
3
1. Post-doctoral Research Fellow, Diabetes Surgery Center; 2. Director of Research for Laparoscopic and Bariatric Surgery,
and Associate Research Professor of Nutritional Sciences in Surgery; 3. Assistant Professor, Chief, Section of Gastrointestinal
Metabolic Surgery, and Director, Diabetes Surgery Center, Department of Surgery, Weill Cornell Medical College
Incretin Mimetics
The Incretin System and Type 2 Diabetes 57
Anthony H Barnett, MD
Professor of Medicine, Consultant Physician, and Clinical Director of Diabetes and Endocrinology,
University of Birmingham and Heart of England NHS Foundation Trust
DPP-4 Inhibitors
Dipeptidyl Peptidase-4 Inhibitors and the Management of Hyperglycemia 63
Pamela M Katz, MD
1
and Lawrence A Leiter, MD
2
1. Resident, Division of Endocrinology and Metabolism, University of Toronto;
2. Head, Division of Endocrinology and Metabolism, St Michael’s Hospital, and
Professor of Medicine and Nutritional Sciences, University of Toronto
Drug Profile—Saxagliptin, a Novel Dipeptidyl Peptidase-4 Inhibitor for the
Treatment of Type 2 Diabetes 70
Baptist Gallwitz, MD, PhD
Professor of Medicine, Department of Medicine IV, Eberhard Karls University of Tübingen
SGLT2 Inhibitors
The Importance of Reducing Hyperglycemia While Preserving Insulin Secretion—
The Rationale for Sodium-coupled Glucose Co-transporter 2 Inhibition in Diabetes 75
Serge A Jabbour, MD, FACP, FACE
Associate Professor of Medicine, and Interim Director, Division of Endocrinology, Diabetes, and
Metabolic Diseases, Jefferson Medical College, Thomas Jefferson University
Type 1 Diabetes
Type 1 Diabetes—Pathogenesis, Prediction, and Prevention 79
Peter R Baker II, MD
1
and George S Eisenbarth, MD, PhD
2
1. Fellow, Clinical Genetics and Metabolism, University of Colorado Denver;
2. Executive Director, Barbara Davis Center for Childhood Diabetes, University of Colorado Denver
Inflammation in Pediatric Patients with Type 1 Diabetes—
An Early Predictor of Complications? 85
Janet K Snell-Bergeon, PhD, MPH
1
and Dana Dabelea, MD, PhD
2
1. Assistant Professor of Pediatrics, Barbara Davis Center for Childhood Diabetes;
2. Associate Professor, Colorado School of Public Health, University of Colorado Denver
Diabetes and Cardiovascular Risk
How Should Diabetes Be Treated to Minimize the Risk of
Cardiovascular Complications? 90
Saul M Genuth, MD
Professor of Medicine, Division of Molecular and Clinical Endocrinology, School of Medicine,
Case Western Reserve University
Cardiovascular Risk in Type 2 Diabetes—Reflecting on the ADVANCE Study 95
Sophia Zoungas, MD, PhD,
1
John Chalmers, MD, PhD
2
and Anushka Patel, MD, PhD
3
1. Senior Research Fellow, Cardiovascular and Renal Divisions, The George Institute for International Health,
University of Sydney, and School of Public Health, Monash University, Melbourne; 2. Director, Professorial Unit,
The George Institute for International Health, University of Sydney; 3. Director, Cardiovascular Division,
The George Institute for International Health, University of Sydney
6 US ENDOCRINOLOGY
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