Welcome to the spring edition of European Endocrinology featuring a wide range of review articles across salient areas of research including diabetes, blood-glucose monitoring, endocrine oncology, thyroid disorders, cardiovascular risk, pituitary disorders and testosterone replacement therapy. Lisa Tarnow et al. review current concerns in obstructive sleep apnoea, a disorder associated with many conditions such as cardiovascular disease, coronary heart disease, heart failure, stroke and diabetes. The journal also features four timely articles on endocrine oncology with particular focus on hormone therapy in endometrical carcinoma, current and future treatments in thyroid cancer and improving quality of life in patients with pituitary tumours. Please peruse and enjoy the other articles featured in this journal and do take time to take a look at our eJournal.
Foreword – European Endocrinology, 2013;9(1):5
It is an honour to be invited to write the foreword to what has become, in a few short years, one of the most respectable Endocrine Journals on either side of the Atlantic. I have the privilege to remain one of the relics on the Editorial Board and congratulate myself for being able to keep […]
Incidence of Hypoglycaemia in Patients with Type 2 Diabetes – A Subgroup Analysis from the GINGER study
Hypoglycaemia is a clinically important and potentially dangerous side effect of insulin therapy in patients with Type 2 diabetes mellitus (T2DM).1,2 The basal-bolus insulin strategy has been studied in the Glulisine in Combination with Insulin Glargine in an Intensified Insulin Regimen (GINGER) study in a population with long-standing insulintreated T2DM, with or without metformin, who […]
Blood Glucose Monitoring
Future Perspectives in Glucose Monitoring Sensors
Blood glucose monitoring is fundamental in the management of diabetes and is essential to optimise glycaemic control. Achieving optimal glucose control is important in reducing the risk of significant long-term microvascular (nephropathy, retinopathy) and macrovascular (cardiovascular disease) complications, as well as neuropathy.
Hormone Therapy plus mTOR Inhibitors in the Treatment of Endometrial Carcinoma
Current and Future Perspectives in Thyroid Carcinoma Treatment
Thyroid nodules are a common clinical problem and with the growing use of diagnostic imaging, the number of thyroid nodules identified and undergoing further diagnostic evaluation by fine-needle aspiration biopsy (FNA) is steadily growing. Only 5 % of all thyroid nodules harbour malignancy and thyroid cancer constitutes only 1 % of all epithelial malignancies worldwide […]
The Use of Sorafenib in the Thyroid Cancer
Introduction The patients with metastatic unresectable thyroid cancer, which does not concentrate radioiodine, have the limited possibilities of treatment because there is no effective treatment options in these group of patients.The role of external beam of radiotherapy and chemotherapy is minimal in these cases.
Improving Quality of Life in Patients with Pituitary Tumours
Pituitary tumours are associated with pituitary dysfunction, either hypersecretion (mainly prolactinomas, acromegaly or Cushing’s disease [CD]) or hypopituitarism, due to compression or destruction of normal pituitary cells. They may also cause headache or visual disturbances due to pressure on surrounding structures.
Short-term Withdrawal of Levothyroxine, Induced Increase of Thyroid-stimulating Hormone and an Increase Ratio of Triiodothyronine to Thyroxine
Hypothyroidism is a ubiquitous condition. According to the National Board of Health and Welfare, thyroid-hormone replacement was prescribed to approximately 370,000 individuals in Sweden during 2010. Eighty-three percent were women, representing more than 6 % of the female population.1 Autoimmune thyroiditis is the most predominant cause, but it may also be a consequence of previous […]
Ezetimibe in the Treatment of Patients with Metabolic Diseases
Dyslipidaemia along with hypertension, obesity and cigarette smoking are established risk factors for premature heart disease.1 The third report of the National Cholesterol Education Program Adult Treatment Panel (NCEP ATP III) recommends a low-density lipoprotein cholesterol (LDL-C) goal of <2.6 mmol/l (<100 mg/dl) for patients with high risk of coronary artery disease (CAD) or CAD […]
Benefits and Consequences of Testosterone Replacement Therapy: A Review
Introduction In our increasingly aged population, late-onset hypogonadism (LOH) is an important public health issue with an incidence estimated at 12.3 cases per 1000 person years.1 There is an increased public knowledge of this condition and more patients are approaching their physicians about diagnosis and treatment.
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