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Showing Results for diabetic nephropathies
Dipeptidyl peptidase-4 (DPP-4) is a ubiquitous, multifunctional, 766-amino acid, type 2 transmembrane glycoprotein, which participates in the regulation of metabolic functions, immune and inflammatory responses, cancer growth and cell adhesion.1Â It has two forms: the first is a membrane-bound form, which ...
Chronic kidney disease (CKD) represents one of the greatest future public health challenges due, among other consequences, to its elevated burden on economic and human resources within healthcare systems.1Â Moreover, the rapid growth of type 2 diabetes mellitus (T2DM) results ...
Diabetic nephropathy (DN) was discovered by the British physician Clifford Wilson (1906–1997) and the German-born American physician Paul Kimmelstiel (1900–1970). Their first publication reporting the disease came out in 1936.1 Overt nephropathy secondary to glomerular disease usually occurs 15–25 years after the diagnosis of ...
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