Species of sphingolipids have been associated with prediabetes risk. Dr Samuel Dagogo-Jack (University of Tennessee Health Science Center, Memphis, TN, USA) discusses the outcome of a longitudinal study conducted at the University of Tennessee which followed a diverse cohort of patients who initially presented with ‘normal’ glucose metabolism but bifurcated into two subgroups: those with […]

The key trials in the field of diabetes, including the results of the tirzepatide study, presented at the 82nd American Diabetes Association Scientific Session, June 3-7, 2022, are discussed by Dr Samuel Dagogo-Jack (University of Tennessee Health Science Center, Memphis, TN, USA). Questions:  What were your highlights from the ADA meeting? (0:37) Disclosures: Samuel Dagogo-Jack […]

The RESTORE-G real-world study investigated the intensification strategies following GLP1-RA therapy failure in type 2 diabetes. Dr Riccardo Candido (Diabetes Center District 4, ASUGI, Trieste, Italy) discusses the design of the study, the key findings and the implications for clinical practice. The abstract entitled ‘Treatment Intensification after Glucagon-Like Peptide-1 Receptor Agonists Therapy in Type 2 […]

touchENDOCRINOLOGY spoke to Leslie Kolb (Chief Science Practice and Learning Officer) and Dana Moreau (Senior Product Manager of Danatech) from the Association of Diabetes Care and Education Specialists (ADCES) to discuss the exciting launch of Danatech. This innovative online resource allows healthcare professionals to research and review the latest devices and mobile apps and offers […]

In a 1958 article titled “Treatment of a pituitary dwarf with human growth hormone”, the merits of human growth hormone (GH) as a treatment for GH deficiency (GHD) were outlined by Raben.1 Beyond its use as a treatment for short stature, GH can be used for other manifestations associated with a GH-deficient state. Therefore, establishing a […]

For people with type 1 diabetes mellitus (T1DM) or type 2 diabetes mellitus (T2DM), glycaemic control has been monitored by two key measurements: laboratory-tested glycated haemoglobin (HbA1c) level and the individuals’ self-monitored blood glucose (SMBG) fingerprick testing.1,2 Both of these measurements have significant limitations. HbA1c provides a surrogate assessment of the average glucose levels of the […]

Nutrient-stimulated gastric inhibitory polypeptide (GIP) (known as either gastric inhibitory polypeptide or glucose-dependent insulinotropic polypeptide) or glucagon-like peptide (GLP-1), are secreted by K and L cells, respectively, in the upper segment of the small intestine and throughout the intestine. For the past 10 years, GLP-1 receptor agonists, which are mimetic of incretins, have been used […]

Obesity – a chronic, relapsing, progressive disease that is defined by a body mass index (BMI) of ≥27.5 kg/m2 in Asian populations and ≥30.0 kg/m2 in all other populations – is an epidemic that has spread across the world.1 Recent data from the World Health Organization (WHO) indicate that 59% of adults and almost one in three children […]