An Introduction to Paediatric Endocrinology
Paediatric endocrinology is a complex field incorporating many conditions such as over or under activity of the pituitary, thyroid and adrenal glands, type 1 diabetes and metabolic bone disease that affect the paediatric population. Collaboration between a multidisciplinary team of paediatric endocrinology specialists, adult endocrinologists and specialist nurses is important to ensure coordinated and comprehensive care.
Browse our gallery of video highlights and short articles from the conference hub, providing the latest expert insights from major conferences and peer-reviewed articles from the journal portfolio.
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Paediatric Endocrinology Content
Are Prepubertal Gynaecomastia and Premature Thelarche Linked to Topical Lavender and Tea Tree Oil Use?
touchREVIEWS in Endocrinology. 2023;19(2):60-68
Article highlights Lavender and tree tea oils have in vitro oestrogenic and antiandrogenic activity. It has been postulated that these oils may cause prepubertal gynaecomastia and premature thelarche. The association is based on a small number patients (N=12) described in five publications. Based upon the amount of dermal penetration of the oils or their constituents and the […]
Improving the alpha-mannosidosis patient journey
An expert gives her perspectives on the history and prevalence of alpha-mannosidosis, its diagnosis and treatment options
- Describe the prevalence and natural history of the rare lysosomal storage disorder alpha-mannosidosis (AM)
- Explain how diagnosis of AM may be approached, and describe the methods of disease identification
- Outline current and emerging management and treatment options for patients with AM
The Clinical Septet of Van Wyk–Grumbach Syndrome: A Case Series from a Tertiary Care Centre in Kalyana Karnataka, India
touchREVIEWS in Endocrinology. 2023;19(1):98-102 DOI: https://doi.org/10.17925/EE.2023.19.1.98
Hypothyroidism usually presents with subtle signs and symptoms. Rarely, longstanding juvenile hypothyroidism can manifest as a syndromic diagnosis of Van Wyk–Grumbach syndrome (VWGS).1 VWGS presents as early menarche, thelarche, galactorrhoea, delayed bone ageing and multi-cystic ovaries, along with long-standing primary hypothyroidism.2 Reversal to the prepubertal state is typically seen following the appropriate treatment with levothyroxine. The present […]
Review of the Function of the Hypothalamic–Pituitary–Gonadal Axis in Children and Adolescents with Cancer
touchREVIEWS in Endocrinology. 2022;17(2):122-32 DOI: https://doi.org/10.17925/EE.2022.18.2.122
The development of effective therapies for the management of cancer in childhood has led to outstanding improvements in survival over the past decades. With this, a growing population of childhood cancer survivors are subject to long-term sequelae impacting on health. Endocrine disorders, and especially reproductive function in adulthood, have become an important concern.1 There is a […]
Bradley Miller, ESPE 2022: Advantages of somapacitan versus daily GH in children with GH deficiency
Daily growth hormone (GH) injections can be burdensome for patients and carers. Somapacitan is a long-acting, reversible albumin-binding GH derivative in development for once-weekly administration in patients with growth hormone deficiency (GHD). In this touchENDOCRINOLOGY interview, Prof. Bradley Miller (University of Minnesota, Minneapolis, MN, USA) discusses the challenges of GH therapy in children and the […]
Bradley Miller, ESPE 2022: Once-weekly somapacitan versus daily GH in children with GH deficiency: The REAL 4 trial
The REAL 4 trial is a multicenter, randomized, controlled, double-blind phase 3 study (NCT03811535) to evaluate the efficacy, safety, and tolerability of once-weekly somapacitan vs once-daily growth hormone (GH). In this touchENDOCRINOLOGY interview, Prof. Bradley Miller (University of Minnesota, Minneapolis, MN, USA) discusses the aims, design and results of the REAL 4 trial. The next […]
Uberto Pagotto, ESPE 2022: GLP-1 agonists and other emerging treatments of obesity
Glucagon-like peptide-1 agonists are a class of medications utilized in the treatment of type 2 diabetes and obesity. In this touchENDOCRINOLOGY interview, Prof. Uberto Pagotto (University of Bologna, Bologna, Italy) discusses the impact of glucagon-like peptide 1 agonists on obesity, what other emerging treatments in obesity appear promising. The future direction in obesity research is […]
Uberto Pagotto, ESPE 2022: The global health burden and challenges of obesity
Paediatric obesity is a major threat to health and longevity. Around 7% of children worldwide have early onset severe obesity before the age of 7. In this touchENDOCRINOLOGY interview, Prof. Uberto Pagotto (IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy) discusses the global health burden of obesity as well as the challenged obesity comes with. The […]
Macimorelin Acetate for the Diagnosis of Childhood-onset Growth Hormone Deficiency
touchREVIEWS in Endocrinology. 2022;18(2):84-5 DOI: https://doi.org/10.17925/EE.2022.18.2.84
In a 1958 article titled “Treatment of a pituitary dwarf with human growth hormone”, the merits of human growth hormone (GH) as a treatment for GH deficiency (GHD) were outlined by Raben.1 Beyond its use as a treatment for short stature, GH can be used for other manifestations associated with a GH-deficient state. Therefore, establishing a […]