touchREVIEWS in Endocrinology and US Endocrinology are peer-reviewed, free-to-access, bi-annual, journals that aims to provide insightful and topical articles relevant to the day-to-day practice of busy physicians.
The journals are of interest to physicians, healthcare professionals and researchers across Europe and the US, providing practical advice relevant to the clinical setting on diagnosis and treatment in endocrinology. touchREVIEWS in Endocrinology and US Endocrinology endeavour to support these professionals in continuously developing their knowledge, effectiveness and productivity.
Contemporary Non-hormonal Therapies for the Management of Vasomotor Symptoms Associated with Menopause: A Literature Review
touchREVIEWS in Endocrinology. 2021; 17(2):Online ahead of journal publication
Nearly 75% of all menopausal women experience bothersome vasomotor symptoms, including hot flushes and night sweats.1 Declining levels of estrogen during menopause lead to a narrowing of the central thermal regulatory neutral tone. Minute changes in core body temperature, as little as 0.8 ± 0.99°C, can often trigger sweating and flushing in both perimenopausal and postmenopausal […]
Diagnosis and Clinical Management of Long-chain Fatty-acid Oxidation Disorders: A Review
touchREVIEWS in Endocrinology. 2021;17(2):Online ahead of journal publication
Long-chain fatty-acid oxidation disorders (LC-FAODs) are pan-ethnic, autosomal recessive, inherited metabolic conditions causing disruption in the processing or transportation of fats into the mitochondria to perform beta oxidation.1 In normal metabolism, long-chain fatty acids are bound to carnitine within the cytosol of cells, and transported across the mitochondrial membranes. Within the mitochondria, they are then cleaved […]
Non-alcoholic Steatohepatitis: From Pathophysiology to Clinical Practice
touchREVIEWS in Endocrinology. 2021;1(2):Online ahead of journal publication
Non-alcoholic fatty liver disease (NAFLD) consists of non-alcoholic fatty liver (NAFL) and non-alcoholic steatohepatitis (NASH). It is unclear which specific patients progress from NAFL to NASH and, ultimately, to cirrhosis. However, there is general consensus that, for those patients who do progress to cirrhosis (fibrosis stage 4), there is an increased risk of liver-related complications […]
Congenital Adrenal Hyperplasia Due to 17-α-hydroxylase Deficiency: A Case Report
touchREVIEWS in Endocrinology. 2021;17(2): Online ahead of journal publication
Congenital adrenal hyperplasia is an innate error in the biosynthesis of adrenal steroids, which triggers a wide range of consequences based on the level of the enzyme blockade. A deficiency in the enzyme 21-α-hydroxylase is the most frequent cause, presenting with different degrees of virilization in women, and may or may not present with the […]
Controversies in Gestational Diabetes
touchREVIEWS in Endocrinology. 2021;17(2):Online ahead of journal publication.
Gestational diabetes mellitus (GDM), defined as hyperglycaemia identified after the first trimester of pregnancy that is not clearly overt diabetes, impacts approximately 7% of births in the USA; a percentage that has increased in parallel with the prevalence of both obesity and type 2 diabetes over the past 20 years.1–4 The impacts of GDM include hypertensive […]
Erratum to: Potential Role of Dexamphetamine in the Treatment of Non-alcoholic Fatty Liver Disease: Hopes and Pitfalls
touchREVIEWS in Endocrinology. 2021;1(2): [online only]
In the originally published article, there was an error in the author affiliations, which incorrectly listed Dr Mandeep Singla as affiliated with the Department of Pharmacology at the Government Medical College and Hospital, Chandigarh. Dr Mandeep Singla is affiliated with the Department of Medicine at the Government Medical College and Hospital, Chandigarh, India. This has […]
The DFUC 2020 Dataset: Analysis Towards Diabetic Foot Ulcer Detection
touchREVIEWS in Endocrinology. 2021;17(1):5–11 DOI: https://doi.org/10.17925/EE.2021.17.1.5
Wounds on the feet, known as diabetic foot ulcers (DFUs), are a major complication of diabetes. DFUs can become infected, leading to amputation of the foot or lower limb. Patients who undergo amputation experience significantly reduced survival rates.1 In previous studies, researchers have achieved high accuracy in the recognition of DFUs using machine learning algorithms.2–5 […]
Assessment of Early Markers of Cardiovascular Risk in Polycystic Ovary Syndrome
touchREVIEWS in Endocrinology. 2021;17(1):37–53 DOI: https://doi.org/10.17925/EE.2021.17.1.37
Polycystic ovary syndrome (PCOS) is a heterogeneous syndrome, considered the most common endocrinopathy in women of reproductive age, with a prevalence of 6–8% in premenopausal women.1,2 However, long-term sequelae are extended beyond the reproductive axis, being present from birth to senescence. Consequently, early detection and treatment options are in high demand to prevent long-term complications. This […]
Renal Tubular Acidosis Manifesting as Severe Metabolic Bone Disease
touchREVIEWS in Endocrinology. 2021;17(1):59–67 DOI: https://doi.org/10.17925/EE.2021.17.1.59
Renal tubular acidosis (RTA) is characterized by the impaired ability of the kidneys to absorb filtered bicarbonate or to excrete titrable acid in urine.1 It manifests as normal anion gap (hyperchloremic) metabolic acidosis. RTA may be of four types: type 1 (distal RTA), type 2 (proximal RTA), type 3 (mixed RTA) and type 4.1 Type 1 […]
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