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    An Introduction to Endocrine Oncology

    Endocrine oncology encompasses malignancies of hormone-producing glands such as the thyroid, parathyroid, pituitary and adrenal gland, as well as endocrine tumours of the gastrointestinal tract and pancreas. While some of these malignancies are relatively rare, thyroid cancer is the most commonly diagnosed cancer in people aged 15–29 years. These cancers present a therapeutic challenge as chemotherapy is often ineffective, and the proliferation rate and the mutational load are usually very low. Advances include small-molecule kinase inhibitors, I-124-positron emission tomography and computed X-ray tomography-based selection of optimal therapeutic strategies, peptide receptor radionuclide therapy with somatostatin receptor antagonists, cell-based therapies and novel immunotherapies.

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