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Thyroid gland inside human body. 3D illustration
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Thyroid eye disease (TED), also known as Graves’ orbitopathy, is a complex autoimmune disorder driven by an interplay of immune cells, orbital fibroblasts and tissue remodelling factors that lead to inflammation, oedema and, ultimately, potential vision loss.1 While the disease has historically been challenging to manage, recent therapeutic innovations are reshaping treatment paradigms and offering new […]

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Women & Diabetes takes centre stage in this interview with Zeina Abou Rizk, Founder of DiaLeb. Zeina explores the unique challenges women face in diabetes care, the power of community and advocacy, and how DiaLeb’s annual panel fosters global awareness, education, and meaningful change through lived experiences and expert insights.

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Article Highlights Early use of sodium–glucose co-transporter-2 inhibitors following myocardial infarction was associated with the following factors: Lower hospitalization for heart failure (odds ratio [OR]: 0.75; 95% confidence interval [CI]: 0.62–0.90; p=0.002). Similar cardiovascular deaths (OR: 1.04; 95% CI: 0.83–1.30; p=0.76). Similar all-cause mortality (OR: 1.00; 95% ...

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It is with great pleasure that we present this latest issue of touchREVIEWS in Endocrinology, which brings together a diverse array of high-quality articles focused on the evolving landscape of endocrine disorders. The importance of patient-centred care is exemplified in ...

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Mahima Chillakanti, Elaine Young, April Hopcroft

The prevalence of diabetes during pregnancy is rapidly increasing. In the USA alone, an estimated 1–2% of pregnant women have type 1 diabetes (T1D) or type 2 diabetes (T2D), and an additional 6–9% develop gestational diabetes.1 From 2000 to 2010, the prevalence of gestational ...

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Polycystic ovary syndrome (PCOS) is a multifactorial, multifaceted syndrome that affects women across all ages from adolescence to post-menopause. It is reported to be the most common endocrinopathy in women of the reproductive age group.1 The nature of this syndrome ...

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‘Closed-loop’ systems mark a significant advancement in managing type 1 diabetes. These systems which continuously monitor glucose levels and automatically deliver insulin through a pump, help many individuals with type 1 diabetes maintain optimal glucose levels with greater ease. In this episode, we explore the progress, challenges and impact of these innovative technologies with Endocrinology Clinical Pharmacy Specialist, Dr Diana Isaacs, and highlight their future potential.

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Members of the endocrinology community gathered in Stockholm, Sweden, for the 26th European Congress of Endocrinology (ECE 2024), eager to explore the latest advancements and exchange knowledge and insights. Here are some of the standout abstracts that captured our attention:

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María José Calvo, Heliana Parra, Raquel Santeliz

Gestational diabetes mellitus (GDM) is generally defined as “any degree of glucose tolerance with onset or first recognition during pregnancy”.1 It currently is one of the diseases with the highest morbidity among pregnant women.2 Determining its prevalence has been a ...

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Meliha Melin Uygur, Marta Villanova, Stefano Frara

Acromegaly is a chronic disease caused by an excess of growth hormone (GH) and insulin-like growth factor 1 (IGF-1).1,2 Besides facial and acral changes, systemic complications lead to decreased quality of life and survival rates.3 The primary goal of acromegaly treatment ...

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Osilodrostat, a novel potent oral steroidogenesis inhibitor, has recently been approved for the treatment of adult patients with endogenous Cushing’s syndrome (CS), and Cushing’s disease (CD) not cured by pituitary surgery or in whom pituitary surgery is not ...

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Cornelius J Fernandez, Lakshmi Nagendra, Joseph M Pappachan

There has been an exponential increase in the global prevalence of obesity over the past few decades because of adverse lifestyle choices, such as physical inactivity and overconsumption of macronutrients. The obesity pandemic has contributed to more than 50 different disorders ...

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Cornelius J Fernandez, Lakshmi Nagendra, Mohammed Alkhalifah

Hypertension affects up to 40% of the adult population worldwide,1 and according to the World Health Organization’s 2021 estimates, globally 1.28 billion adults between 18 and 79 years are affected.2 Of these, 85% have essential hypertension3 and the remainder have secondary hypertension, which is potentially ...

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Diabetes mellitus (DM) is a group of metabolic disorders marked by elevated blood glucose. It has many subtypes, including type 1 diabetes mellitus (T1DM), type 2 diabetes mellitus (T2DM), gestational diabetes and neonatal diabetes; of these, T1DM and T2...

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Article highlights Epigenetics refers to the heritable changes in DNA expression without changes in the genetic code. Epigenetic changes are brought about by post-translational modifications of histone proteins, covalent modifications of DNA bases and microRNA. Epigenetics explains how environmental milieu ...

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We caught up with the American Thyroid Association (ATA) president Prof. Julie Ann Sosa, MD, MA, FACS (University of California, San Francisco, CA, USA) ahead of this year’s virtual meeting to highlight their ATA Centennial Celebration at their upcoming ...

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Chylomicronaemia refers to the pathological presence of large, circulating, intestinally derived chylomicrons.1 Clinical features of chylomicronaemia syndrome include lipaemic plasma, lipaemia retinalis, eruptive xanthomas, hepatosplenomegaly, neurological symptoms such as mental fog and mood changes and, most importantly, increased risk of ...

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Clinicians depend on accurate, precise and reproducible hormone measurements for the diagnosis and management of endocrine disorders. Immunoassays have constituted one of the major methods of measuring hormone levels in blood, urine and other fluids, as well as in tissue ...

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Welcome to the latest edition of touchREVIEWS in Endocrinology. The articles in this issue present authoritative, up-to-date information on a wide range of topics, reflecting the scope of the broadening discipline of endocrinology. We begin with four articles on the ...

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