Setmelanotide: A Melanocortin-4 Receptor Agonist for the Treatment of Severe Obesity Due to Hypothalamic Dysfunction
Sulmaaz Qamar, Ritwika Mallik, Janine Makaronidis
Obesity defined as abnormal or excessive fat accumulation that presents a risk to health, is a chronic disease linked to metabolic co-morbidities, such as type 2 diabetes mellitus and cardiovascular disease, a reduced life expectancy, economic burden and reduced quality of life.1 Worldwide obesity rates nearly tripled from 1975 to 2016, with over 650 million adults […]