ADA Highlights

Dr. John Doupis (Director, Iatriko Paleou Falirou Medical Center, Diabetes Division, Athens, Greece; Editor-in-Chief, touchREVIEWS in Endocrinology) provides his top three highlights from the ADA 83rd Scientific Sessions, 2023 in the field of type 2 diabetes. Disclosures: John Doupis has received consultant fees from Elli Lilly, Novo Nordisk, Abbott, Astra Zeneca and Boehringer Ingelheim. He […]

Dr. Carolina Solis-Herrera (Associate Professor of Medicine at the University of Texas Health San Antonio (UTHSA) and Chief of Endocrinology Division) provides an overview of their presentation: Empagliflozin Improves Cardiopulmonary Function and VE/VCO2 in Patients with T2D and HFrEF at ADA 83rd Scientific Sessions, 2023. Questions: What led to the hypothesis that empagliflozin might be […]

Prof. Chantal Mathieu (Katholieke Universiteit Leuven, Belgium) provides her highlights from the ADA 83rd Scientific Sessions, 2023 including Teplizumab, an anti-CD3 monoclonal antibody, which was the first disease modifying therapy that delays the progression from stage 2 to stage 3 type 1 diabetes and was FDA approved in November 2022; Orforglipron, an oral, non-peptide glucagon-like […]

The CLEAR Outcomes trial was a double-blind, randomized, placebo-controlled trial involving patients who were “statin-intolerant” and had, or were at high risk for, cardiovascular disease. The patients were assigned to receive oral bempedoic acid, 180 mg daily, or placebo. Dr. Steven Nissen (Heart, Vascular and Thoracic Institute, Cleveland Clinic Center for Clinical Research, Cleveland, OH, […]

Orforglipron (LY3502970) is a novel oral non-peptide GLP-1 receptor agonist being developed for patients with obesity or overweight, particularly those with type-2 diabetes. Dr. Sean Wharton (Adjunct Professor at McMaster University and Medical Director of the Wharton Medical Clinic) discusses the Phase 2 study, including likely clinical impacts, and future directions following these findings. The […]

The RESTORE-G real-world study investigated the intensification strategies following GLP1-RA therapy failure in type 2 diabetes. Dr Riccardo Candido (Diabetes Center District 4, ASUGI, Trieste, Italy) discusses the design of the study, the key findings and the implications for clinical practice. The abstract entitled ‘Treatment Intensification after Glucagon-Like Peptide-1 Receptor Agonists Therapy in Type 2 […]

Intensification strategies are available if patients with type 2 diabetes experience GLP1-RA therapy failure. Dr Riccardo Candido (Diabetes Center District 4, ASUGI, Trieste, Italy) discusses the current place of GLP1-RA therapy for the treatment of type 2 diabetes and the intensification strategies available following failure. Dr Riccardo Candido presented an abstract entitled ‘Treatment Intensification after […]

The key trials in the field of diabetes, including the results of the tirzepatide study, presented at the 82nd American Diabetes Association Scientific Session, June 3-7, 2022, are discussed by Dr Samuel Dagogo-Jack (University of Tennessee Health Science Center, Memphis, TN, USA). Questions:  What were your highlights from the ADA meeting? (0:37) Disclosures: Samuel Dagogo-Jack […]

There has been an update to the guidelines, which shows a shift towards target organ protection being the primary consideration when treating patients with diabetes. Dr Samuel Dagogo-Jack (University of Tennessee Health Science Center, Memphis, TN, USA) discusses the updates to the guidelines presented at the 82nd American Diabetes Association Scientific Session, June 3-7, 2022. […]