A cure for diabetes remains the ultimate aim for many diabetes researchers. Advances in closed loop/artificial pancreas (CL/AP)
therapy and stem-cell research are bringing some hope for patients with type 1 diabetes. Better understanding of the nutrients effect
on diabetes and body weight may also open new venues for prevention and management of type 2 diabetes. Ilkowitz and Ranchandani
review the CL/AP system including recent studies on multi-hormonal CL/AP treatments, exercise and dining out. Several editorials in
this issue tackle other aspects of diabetes care such as the role of exercise and weight loss and the emergence of youth-onset type 2
diabetes. Of particular concern are cross-generational effects, with rising rates of pre-gestational exposure to diabetes a risk factor for
the development of type 2 diabetes in people under the age of 18. In addition, a timely overview of obesity medicine and the underlying
physiology and pathophysiology is presented by Gonzalez-Campoy.
The application of the New American Thyroid Association Treatment Guidelines in clinical practice is illustrated through a synopsis of a
wide variety of cases of children and adolescents with thyroid cancer, presented by Bauer et al.
Scalp hair thinning (SHT) can be one of the most distressing symptoms for women with polycystic ovary syndrome (PCOS). Ikhena et
al present data from a cross sectional study identifying SHT as a phenotypic reflection of the concomitant metabolic burden in PCOS.
Abnormal two-hour oral glucose tolerance test, serum low-density lipoprotein, and skipped meals were independent predictors of SHT in
women with PCOS in this analysis.
US Endocrinology is grateful to all the contributors to this edition, from organizations to individuals. Special thanks, as always, goes to the
Editorial Board for their invaluable support and guidance. We welcome feedback from readers on the articles from this issue and on topics
and controversies that you would like to see covered in the future.