Diabetes is an enormous health burden worldwide, and the current epidemic of type 2 diabetes is of paramount concern. The most important recent advances in the management of type 1 diabetes have been immunotherapies, designed to delay disease onset and the development of fully automated artificial pancreas systems that integrate blood glucose monitoring and insulin delivery. In type 2 diabetes, the widespread use of DPP-4 inhibitors, GLP-1 receptor agonists and SGLT-2 inhibitors have facilitated optimal glycaemic control without increased risk of hypoglycaemia and weight gain. Emerging data from cardiovascular outcome trials have shown that these agents can reduce the risk of cardiovascular disease in high-risk individuals.
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Expert insights into the future of ketone monitoring to prevent diabetic ketoacidosis
Type 2 diabetes (T2D) is a progressive metabolic condition associated with obesity, cardiovascular disease and substantial morbidity and mortality.1 Despite the availability of multiple glucose-lowering therapies, a significant proportion of individuals with T2D fail to achieve recommended glycemic targets, ...
Achieving clinically meaningful weight loss and cardiometabolic targets is a key goal in the management of obesity and type 2 diabetes, particularly in people at elevated cardiovascular risk. In this analysis of the phase 3 STEP UP T2D trial, researchers evaluated the extent to which participants treated with semaglutide 7.2 mg, semaglutide 2.4 mg or placebo achieved predefined BMI, waist-to-height ratio and cardiometabolic targets after 72 weeks. In this interview, Prof. Carel le Roux discusses the rationale for assessing these treatment targets, the key findings from the analysis and their implications for the use of higher-dose semaglutide in people with obesity and type 2 diabetes.
At ECE 2026, Evelien Gevers discussed data showing DCCR reduced hyperphagia in Prader–Willi syndrome and remained generally safe in patients with pre-diabetes or diabetes, supporting broader clinical confidence and access.
Data presented at ENDO 2026 highlighted investigational approaches for difficult-to-control type 2 diabetes and acquired hypothalamic obesity, real-world outcomes with tirzepatide, and wider health impacts of GLP-1-based therapy.
Adults with prediabetes who received an intensive lifestyle intervention in the Diabetes Prevention Program were less likely to develop multiple chronic conditions over long-term follow-up than those assigned to placebo, according to an analysis published in JAMA.1 A similar reduction was not observed with metformin.
The FDA has granted accelerated approval to teplizumab-mzwv to delay the decline in endogenous insulin production in children aged 8–17 years recently diagnosed with stage 3 type 1 diabetes (T1D).1 The approval marks the first disease-modifying treatment option for this population.
In this interview, Diana Isaacs shares her highlights from the 2026 AACE Annual Meeting, discussing key advances in diabetes management, obesity treatment and diabetes technology, alongside emerging priorities for future endocrinology research and guideline development.
Welcome to the summer 2026 issue of touchREVIEWS in Endocrinology. In this issue, we bring together articles that reflect the evolving complexity of endocrine and metabolic disease, while highlighting the growing importance of patient-centred care, translational science and interdisciplinary management. We ...
Omnipod 5 real-world case studies.
Using Omnipod 5 for exercise.
New data presented at the Advanced Technologies & Treatments for Diabetes 2026 highlight a shift in diabetes care beyond glucose control alone. Emerging evidence supports the growing role of incretin-based therapies such as semaglutide, alongside advances in continuous glucose monitoring systems including Dexcom G7 and Freestyle Libre 3. Together, these innovations demonstrate meaningful improvements in glycemic outcomes, cardiometabolic risk, and patient behaviors, signaling a move toward more personalized, integrated approaches to diabetes management across both type 1 and type 2 diabetes.
Urinary lithogenesis processes are activated in patients with obesity, metabolic syndrome (MetS), and type 2 diabetes (T2D). This is a relatively unfamiliar topic among endocrinologists. Beyond the epidemiological evidence accumulated over the recent years, the purpose of this paper is ...
The past century has witnessed substantial evolution in the assessment and management of type 1 diabetes (T1D), paralleling advances in our understanding of the condition and in innovation in technology. Since the ground-breaking discovery of insulin in the 1920s, T1...
The European Association for the Study of Diabetes (EASD) Early Career Academy (ECA) has rapidly become a central initiative supporting the professional development of emerging clinicians and researchers in diabetology. Established to foster mentorship, collaboration and career progression, the Academy ...
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