Welcome to the winter edition of US Endocrinology, which features a wide range of topical articles covering a number of areas of endocrinology and metabolism. We discuss topics including, the effect of circadian rhythm on skeletal muscle insulin sensitivity, the findings of the REWIND study and the COMISAIR study, their clinical implications and the latest developments in continuous glucose monitor.
Kalra et al. present an approach to integrating person-centered care into diabetes care and Modzelewski et al. report on the need for patient-reported outcomes when evaluating mobile wireless technology in diabetes. Hossein Gharib et al. provide a comprehensive review of the latest developments in molecular testing in thyroid practice and provide information on the current molecular methods available for diagnostic and prognostic purposes applied to thyroid nodules.
The American Association of Clinical Endocrinologists (AACE) is the world’s largest organization representing clinical endocrinologists. In an editorial, President Sandra Weber discusses the ways in which the organization is evolving to meet the demands of the changing treatment landscape. Elizabeth Pearce, President of the American Thyroid Association (ATA), also shares the recent activities and future plans of the ATA, as well as discussing their aim of ‘optimal thyroid health for all’.
We hope that you will find plenty of interest among this issue.
Foreword – US Endocrinology 15.2 Winter 2019
Welcome to the winter edition of US Endocrinology, which features a wide range of topical articles covering a number of areas of endocrinology and metabolism that have relevance to the wider biomedical community. This issue begins with one of our popular expert interviews. A growing body of evidence suggests that the circadian clock affects the development […]
Circadian Rhythmicity of Skeletal Muscle Metabolism
There is increasing evidence to support the association between the circadian clock and the development of metabolic diseases.1 Misalignment of circadian rhythm can increase insulin resistance and decrease pancreatic function.2 Such disruptions may increase the likelihood of developing type 2 diabetes mellitus (T2DM).1,3 The effects of natural rhythm disruptions have been highlighted in increased T2DM risk in people […]
American Association of Clinical Endocrinologists—Update for 2019
American Association of Clinical Endocrinologists (AACE) is the world’s largest organization to represent clinical endocrinologists with more than 6,900 members in the USA and 99 other countries. Members have access to educational programs, subscriptions to AACE publications, discount registration to AACE Annual Scientific & Clinical Congress, scholarship and grant opportunities, advance notice of endocrine job opportunities, […]
The American Thyroid Association—What’s New in 2019
The American Thyroid Association 89th annual meeting The ATA’s 89th annual meeting will be held at the Sheraton Grand in Chicago, IL, USA, from October 30 to November 3, 2019. The meeting program this year is co-chaired by Dr Antonio Di Cristofano and Dr Mona Sabra. It is designed to cover the latest developments in both […]
Once-weekly Dulaglutide and Major Cardiovascular Events—Results of the REWIND Trial
Cardiovascular outcome trials (CVOTs) have become mandatory for glucose-lowering drugs in the treatment of patients with type 2 diabetes (T2D) since 2008, following the withdrawal of rosiglitazone from the market because of its association with increased risk of cardiovascular disease (CVD).1 In subsequent years, results have emerged from several CVOTs, with many more underway, all demonstrating […]
Continuous Glucose Monitoring for Diabetes Management—Current Status and Future Perspectives
Despite significant advances in technologies for the management of patients with type 1 diabetes (T1D), outcomes remain suboptimal across all age groups.1 Achieving glycemic control in patients with T1D requires precise and accurate methods of delivering insulin and monitoring blood glucose. The introduction of insulin analogues, with rapid and prolonged durations of action has allowed for […]
The 6E Approach to Person-centered Care
Person-centered care Person-centered care is a complex construct, with multiple facets to it. While the definition of person-centered care, or patient-centered care, is relatively straightforward, the practice of person-centered care is not easy. The Institute of Medicine defines person-centered care as “care that is respectful of and responsive to individual patient preferences, needs, and values” […]
Reconsidering Meaningful Outcomes in Diabetes mHealth Research
Technology has played a significant role in diabetes care for more than 50 years, from the advent of the original insulin pump to more recent artificial pancreas technologies. In healthcare more broadly, the use of technology through digital health has gained traction over the last 20 years, with interest expanding to mobile wireless technology, or […]
Molecular Testing in Thyroid Practice
Thyroid nodules are common and frequently benign, with approximately 5–10% being malignant.1 Current diagnostic evaluation of thyroid nodules should include a multidisciplinary approach, integrating clinical, sonographic, cytologic, and molecular analysis. While fine-needle aspiration (FNA) biopsy and cytologic examination have emerged as the gold standard in separating benign from malignant nodules, cytology is limited and challenging when […]
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